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The Sharon Laboratory
at the Department of Ophthalmology
Hadassah - Hebrew University Medical Center
RESEARCH
The Sharon lab at Hadassah studies Inherited retinal diseases. This large group of diseases is caused by mutations in many different genes. Currently, we estimate that mutations in over 300 genes can cause human retinal diseases, including retinitis pigmentosa (RP), cone-rod degeneration (CRD) , Stargardt disease, Best disease, and achromatopsia (ACHM).
The Sharon lab focuses on three aspects of inherited retinal diseases:
1. Identification of genes and mutations that cause inherited retinal diseases in the Israeli and Palestinian populations.
2. Deciphering the mechanisms that cause retinal disease and degeneration.
3. Developing gene-based therapeutic modalities to treat inherited retinal diseases.
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